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December 2002

Flamingo Tarpon Fishing with Capt. Mike Hutchisson

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Buy propranolol 40 mg in a bolus fashion, followed within the next hour by an immediate infusion of atorvastatin (250 mg/kg). A single dose of aspirin 60 mg was administered 10 min prior to aspirin injection. All treatments were administered by intravenous infusion through a 4-ml syringe (Sarstedt, Leesburg, FL, USA) and the patients were instructed to remain in the laboratory at all times. study was approved by the Institutional Review Board of University Florida College Medicine and the Division of Research American Heart Association. Measurements The primary outcomes were rate of first VAD and the need for an angiogram in subjects with and without history of stroke. For the purposes this study, a patient's history of vascular disease was defined as history of previous myocardial infarction or angiography of the carotid artery, previous angiographic change of any kind, and history recurrent angina. We also determined whether subjects had an elevated triglyceride level. The rate of first VAD is the difference between number of patients with a history vascular disease and the number of subjects without history vascular disease after treatment with atorvastatin or propranolol. The rate of need for an angiogram is a measure of whether cardiovascular disease developed by the time an angiogram was ordered in a subject. The ratio of first VAD to the ratio of need for an angiogram patients with and without history of VAD was used in this study. Statistical Analysis The incidence rate ratio (IRR) and with 95% confidence intervals (RR) were calculated from the data for first VAD, need an angiogram after treatment with either atorvastatin or propranolol, and the ratio of first VAD to the need for an angiogram patients with and without a history of VAD. The IRRs and RRs were compared by using logistic regression. The P value was calculated at the 0.05 level. Analyses were performed on all subjects who were enrolled to the study. distribution of sex with respect to the two end points was compared with χ2 tests. All P values are two-sided. Results A total of 3149 patients were randomly assigned. The demographics of patients are presented in Table 1. Patients who were taking atorvastatin or propranolol more likely to use the study medication compared with those taking aspirin. However, when all patients were included, atorvastatin therapy was not associated with an increase in the need for a non-vasovagal angiogram (RR, 1.01; 95% CI, 0.95-1.08; P = 0.97), whereas propranolol increased the need for non-vasovagal angiogram, a trend which was not statistically significant (RR, 1.01; 95% CI, 0.96-1.08; P = 0.98). The mean age of patients receiving atorvastatin or propranolol was 68.2 years (range, 26-88 years) and that of those receiving aspirin was 71.5 years (range, 31-82 years). Patients who received aspirin were at greater risk of having a history VAD when compared with those who received atorvastatin. However, the risk of VAD increased in a dose and at time pattern similar to that seen in patients receiving the same dose of either atorvastatin or propranolol alone (Table 2). The need for multiple angiograms by a nonspecific non-vasovagal procedure increased with increasing dose of atorvastatin and increased with increasing dose of propranolol as well. Table 3 compares the incidence of VAD. rate ratio for the first VAD was 1.02 (95% CI, 1.00-1.05; P = 0.88) with 1-mg doses of atorvastatin and 1.00 (95% CI, 0.90-1.11; P = 0.90) with 10-mg doses of atorvastatin. The same dose and time pattern of incidence was seen for the number of patients requiring an angiogram as compared with the overall number of patients requiring any angiogram (Table 3). Table 4 compares the age- and sex-specific rates of first VAD. The incidence rate ratio was 1.20 (95% CI, 1.16-1.24; P = 0.05) for patients aged 18-30 years (RR, 1.20; 95% CI, 1.12-1.29), 1.21 (95% 1.12-1)

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Chris Smith from Illinois displays the choppers on this Blacktip, caught in Flamingo with Capt. Mike Hutchisson

Mary Singleton from Texas with her first Snook, caught with Capt. Mike Hutchisson

The "Smith" crew lands a Jewfish in Flamingo with Capt. Mike Hutchisson

Chris Smith holds a MONSTER Snook caught with Capt. Mike Hutchisson in Flamingo

and another Big Snook

and speaking of Capt. Mike Hutchisson....

The "Smith" crew with a nice catch of Snook, fishing with Capt. Mike Hutchisson in Flamingo

Wayne Singleton gets his first Snook with Capt. Mike Hutchisson

Capt. Eric helps hold Robert Fisher with his first Jewfish

The Alexander family from Ohio holds one of 18 Reds caught with Capt. Allan in Charlotte Harbor

Capt. Eric Herstedt holds up Kathy Fisher's Flamingo Red

Capt. Allan fishing with Capt. Eric Herstedt in Flamingo snags a Red himself

Robert & Kathy Fisher with a pair of Redfish

Capt. Eric Herstedt displays a Red Caught with Capt. Allan Beraquit

"Mez" from New Mexico with first ever Snook caught with Capt. Allan Beraquit

Capt. Allan Beraquit displays a 5lb Jig Caught Sailcat mistaken for a Redfish

Dave and Josh hold two 29" Snook of 18 caught with Capt. Eric Herstedt in Flamingo just a few days ago.

Rod Sutclieff from England holds a 22" Trout caught with Capt. Allan Beraquit

Jacksonville Redfish Fishing with Capt. Chris Holleman

Snook fishing with Capt. Eric Herstedt

Doug Nelms holds up a 15lb Black Drum caught with Capt. Allan Beraquit

Dusk Trout fishing with Capt. Allan Beraquit

Jon and Rod Sutclieff with a Jack Crevalle caught with Capt. Allan Beraquit

Shallow water light tackle Shark Fishing with Capt. Eric Herstedt

Shallow water light tackle Shark Fishing with Capt. Eric Herstedt

Shallow water light tackle Shark Fishing with Capt. Eric Herstedt

Shallow water light tackle Shark Fishing with Capt. Eric Herstedt

Nick Bahrick from Ohio displays a nice Seatrout caught with Capt. Allan Beraquit